Unfortunately, almost all drugs have the potential to cause some type of allergic and immunogenic response. However, what are the prevalence of these reactions with peptides? “Biological drugs” are a class of medication which are partially or completely chemically constituted by amino acids that are linked to each other forming peptides and proteins. The basic distinguishing factor between peptides and proteins are size and structure. Traditionally, peptides are much smaller compared to proteins; consisting of 2-50 amino acids while proteins are made up of 50 or more. Further, peptides tend to be less defined in structure than proteins as proteins can adopt complex conformations known as secondary, tertiary, and quaternary structures. Proteins tend to give cells their shape and respond to signals transmitted from an extracellular environment. peptides play key roles in regulating the activities of other molecules. Although the differences between proteins and peptides are subtle, there may be an...

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