



MUFAs save lives! … SFAs not so much The European Prospective Investigating into Cancer and Nutrition (EPIC) is one of the largest cohort studies in the world, with more than half a million (521,000) participants recruited across 10 European countries and followed for almost 15 years. In order to determine how substitution of dietary carbohydrates with different fats was related to all-cause and cardiovascular disease (CVD) –specific mortality, Campmans-Kuijpers et al crunched the numbers on the entire EPIC sub-cohort of individuals with diabetes (n=6192). Substituting 5% of calories from carbohydrates with total and saturated fat led to an 8 and 29 % greater risk of all-cause mortality, respectively, but had no effect on CVD-specific mortality. On the other hand, substituting for polyunsaturated fats increased the risk of CVD-specific mortality by 37% and tended to increase all-cause mortality risk by 20%! Keep in mind that no differentiation between types of polyunsaturated fats...


